Relationship between the higher inflammatory cytokines level in the aqueous humor of Fuchs uveitis syndrome and the presence of cataract

Abstract Background This study aims to compare the levels of intraocular cytokines between Fuchs uveitis syndrome (FUS) eyes and senile cataract eyes. The association inflammatory cytokine severity in FUS is evaluated find possible mechanism Methods A retrospective 28 with was performed. Auxiliary examinations were performed, including ophthalmic examinations, laser flare-cell photometry, aqueous humor measured. control group included 25 cataract. Data on compared two groups. posterior subcapsular assessed. Results There 27 patients. Unilateral involvement noted 26 patients (96.30%). Stellate keratic precipitates (KPs) 16 (57.14%). Heterochromia observed 21.43% affected Posterior (PSC) Eyes had significantly higher (AH) (VEGF, bFGF, IL-6, IL-8 IL-10) ( P < 0.05). a statistically significant positive correlation IL-6 AH (? = 0.664 0.634, respectively; 0.001, 0.002, respectively). Conclusions Expression VEGF, IL-10 than eyes, positively associated Our results imply that an inflammation may be involved early development FUS.